St. John’s wort is also known as Hypericum perforatum, klamath weed, John’s wort, amber touch-and-heal, goatweed, rosin rose, and milleperituis. St. John’s wort has been used in the treatment of anxiety, mild to moderate depression, stomach upset, insomnia, fluid retention, and hemorrhoids. St John’s Wort is traditionally used to support healthy mood and promote emotional well-being. Numerous clinical trials have studied the efficacy of St John’s Wort in this capacity, with most of them showing positive results that are comparable to conventional treatments. St. John’s wort has also been studied for the treatment of other emotional disorders such as obsessive-compulsive disorder (OCD), menopausal mood swings, and premenstrual syndrome. In laboratory studies, it has shown some effectiveness for lessening the symptoms of nicotine withdrawal and for reducing the craving for alcohol in addicted animals. It is believed that chemicals in St. John’s wort may act like other chemicals that are associated with relieving emotional conditions.